Fine Needle Aspiration Cytomorphological Spectrum (FNAC) Of Peripheral Lymph Node Lesions At A Tertiary Care Teaching Medical College & Hospital

Introduction: Peripheral lymhadenopathy is common presentation of inflammatory and neoplastic lesions.FNAC is one of the first–line investigations of managenent for the evaluation of lymphadenopathy.Enlargement of Lymph node is seen in variety of reactive inflammatory to neoplastic conditions related to regional or systemic diseases. It is very useful, easy, rapid, minimal invasive, cost effective and accurate approach in diagnosing various lymph node lesions and helpful in the workup of management of patients with nodal enlargement. Methods: A total of 175 patients were included in our study Department of Pathology, referred from the department of ENT, Medicine, Paediatrics, Surgery, Respiratory Medicine and Tuberculosis of Karpaga Vinayaga Hospital in the period from January 2017 to Dec 2018. Alcohol fixed and air dry smears were prepared and stain with H&E, PAP, and MGG. The special stain like PAS, ZN (20%) etc were done whenever required. Results:In present study total 175 cases of lymphadenopathy were studied. The presentation of various lymph node lesions on cytomorphological findings were Acute non–specific lymphadenitis cases were 5 (2.85%), Chronic non–specific lymphadenitis cases were 11 (8.28%), Granulomatous lymphadenopathy cases were 6 (3.42%), Tuberculous lymphadenitis cases were 60 (34.28%)’ Reactive lymphadenitis cases were 48 (27.42%), Metastasis to lymph node cases was 36 (20.57%), Lymphoma cases were 9 (5.14%). Unsatisfactory smears(11) were excluded from the study. The detailed clinical material data, relevant investigations were taken for supporting the diagnosis. Conclusion: Cytomorphological features of lymph node FNAC, used in conjunction with clinical details, laboratory test investigations, radiology imaging study will be very helpful for diagnosing various disorders. It will be rapid, cost effective, safe, and reliable method for early diagnosis and treatment of the patients

Fine Needle Aspiration Cytopathology (FNAC) Of Thyroid Lesions Reporting As Per Guidelines Of Recent Bethesda System At A Tertiary Care Teaching Medical College & Hospital

Introduction: Estimation of accuracy of ne needle aspiration cytopathology (FNAC) of thyroid in diagnosis of different thyroid lesions, and evaluation of the value of reporting FNAC per guidelines of Bethesda system in reducing the number of un necessary thyroidectomies. This is a case control prospective study conducted on 54 patients with thyroid nodules. Patient were recruited to Cytopathology Department, KIMS Teaching Hospital in the period from January 2017 to December 2018. Results of FNAC were reported per recent Bethesda System for Reporting of Thyroid Cytopathology (TBSRTC). Reporting of Thyroid Cytopathology (TBSRTC) diagnoses were determined to be very useful for surgical removal thyroid tissues. Methods: The current study was a retrospective study on 54 patients with thyroid swelling referred to the Department of Pathology, Karpaga Vinayaga Hospital in the period from January 2017 to Dec 2018. Cases included in the present study were those with preoperative FNAC and The data of 54 cases with enlarged thyroid glands that were referred to our cytolaboratory in this period. Thyroid swellings were aspirated using disposable needles using standard procedures. The aspirated contents of needles were expelled onto the glass slides. Slides were immediately xed in methanol and smears were stained with papanicolau and hematoxlin and eosin stains whereas slides were air dried before staining it with giemsa Results: Out of 54 cases, Bethesda category I included 3 cases (5.5%), category II constituted 42 cases(77.7%) out of which 22 cases (52.38%) were benign follicular nodule type II, 13 cases(30.95%) were colloid nodule, 7 cases (16.7%) were hashimoto thyroiditis, category III (AUS) included 2 cases (3.70%), category IV (Follicular Neoplasm) had 4 cases(7.40%), category V (Suspicious of malignancy) included 2 cases (3.70%), category VI (malignant) constituted 1 case (1.85%). Male to female ratio was 1:6.9. Highest prevalence was noted in 30-40 years of age. Conclusion: Fine needle aspiration cytopathology from thyroid nodule(s) is a safe, quick outpatient, cost effective and easy procedure if done by expert hands, but it needs a unied system of interpretation, reporting language and guidelines for proper categorization and management. Bethesda System for Reporting Thyroid Cytopathology is a comprehensive system for cytopathological diagnosis of thyroid nodule(s) and with strict diagnostic criteria for each category, predicting risk of malignancy and guidelines for planning of further management. Thyroid Fna can play a pivotal role in the management of patients with thyroid nodules by Bethesda system directly confers risk of malignancy in each category which in turn prompts the recommended clinical management of that category thus establishing an excellent clinico-pathological corelation. providing clinicians with a clear and comprehensible cytopathology reports. The Bethesda system is very useful for a standardized system of thyroid cytopathology reporting, best communication between clinicians and cytopathologists , leading to more consistent management approaches